Yearly Archives: 2016

   Read: His tagged cryocapture – Langmuir 2016 The Center for Integrative Chemical Biology and Drug Discovery Presents: David H. Thompson, PhD Professor – Organic Chemistry Purdue University   “Development of New Tools for Accelerated Protein Structure Determination and Reaction … Read more

Thanks to the North Carolina Biotechnology Center Institutional Development Grant (NCBC IDG) program, the CICBDD and the Hooker Imaging Core were awarded $200,000 to support the purchase of a high content cell imaging system.  Matching funds for the instrument were … Read more

October 6, 2016 By David Etchison The University of North Carolina at Chapel Hill will pursue treatments for specific cancer targets as a specialized member of the National Cancer Institute’s renewed Experimental Therapeutics, or NExT, program. Because of its unique … Read more

R01 Stephen Frye, PhD and Lindsey James, PhD will collaborate with PI Matt Redinbo, PhD on his R01 grant from NCI entitled Microbiome-Targeted Probes to Eliminate Chemotherapy-Induced GI Toxicity.  The overarching hypothesis is that microbial enzymes expressed by the GI … Read more

Rob was born in Muscatine, Iowa, and adds “but spent all of my school age years in Portland, Oregon. Since then I have been an academic nomad with undergraduate studies at Iowa State University followed by graduate work in the … Read more

Kimberly Diane Barnash, Kelsey N Lamb, Jacob I Stuckey, Jacqueline L. Norris-Drouin, Stephanie H Cholensky, Dmitri B. Kireev, Stephen V. Frye, and Lindsey I. James ACS Chem. Biol., Just Accepted Manuscript DOI: 10.1021/acschembio.6b00415 Publication Date (Web): June 29, 2016 Copyright … Read more

Thanks to the North Carolina Biotechnology Center Institutional Development Grant (NCBC IDG) program, the CICBDD and the Hooker Imaging Core were awarded $200,000 to support the purchase of a high content cell imaging system.  Matching funds for the instrument were … Read more

March 21, 2016 By Laura Oleniacz, UNC Lineberger Comprehensive Cancer Center Read the entire article here .

Story by Susan Hudson, University Gazette Video by Carly Swain, Office of Communications and Public Affairs Published March 30, 2016   Read the article in its entirety here. http://www.unc.edu/spotlight/pharmacy-school-celebrates-top-ranking/

Dr. Sarah Scarry was appointed to the position of Research Assistant Professor in the Division of Chemical Biology and Medicinal Chemistry in the UNC Eshelman School of Pharmacy.  Dr. Scarry will be expanding her medicinal chemistry expertise into the arena … Read more

On March 16, 2016, Dave Etchison writes, “The UNC Eshelman School of Pharmacy is number one in the latest rankings by U.S. News & World Report of the nation’s Doctor of Pharmacy programs in the 2017 edition of “America’s Best … Read more

February 16, 2016 an IND was opened for clinical trials of MRX2843 (UNC2371) in patients with solid tumors. On March 1, 2016 a patent was issued for UNC2371 (MRX2843 as licensed to Meryx Inc., http://meryxpharma.com/home).  The inventors Xiaodong Wang, Jing … Read more

Using New Screening Tool, UNC Researchers Identify Potential Treatments for Ewing Sarcoma March 1, 2016 By Laura Oleniacz, UNC Lineberger Comprehensive Cancer Center Stephen Frye, Ph.D., directs the School’s drug discovery center, which played a key role in the recent … Read more

  Jacob Stuckey (PhD Candidate 2016) and colleagues report in Nature Chemical Biology the first cellularly active chemical probe (UNC3866) for any member of the chromodomain family of proteins that recognize, or “read” methylated lysine.  Specifically, the probe inhibits the … Read more

On December 1, 2015, Dr. Samantha Pattenden received word that she is the recipient of a $7500 IBM Junior Faculty Development Award. Congratulations!

We are pleased to announce that our very own Nate Hathaway has been named a 2016 recipient of the AACP New Investigator Award. Nate’s award centers around the “Development of Novel Inhibitors of Mammalian Heterochromatin Gene Repression.”  View all the … Read more

Lindsey James, Steve Headey (Monash University, Australia), Ken Pearce and Stephen Frye have been awarded a grant by the PharmAlliance Research Working Group and Deans to assist in funding preliminary data for the project “Discovery of Inhibitors for the Methyl-Lysine … Read more

  Ken Pearce and collaborator Channing Der (Pharmacology) received a UNC Lineberger Development Research Grant for their proposal, “A Cellular Screen Utilizing the Global Protein Stability Method to Identify Chemical Probes that Expedite the Myc-degradation Pathway.” (Jan. 2016)

The Center for Integrative Chemical Biology and Drug Discovery welcomes Jichen Zhao to the Medicinal Chemistry Group and Gwonchan Yoon to the Computational Biophysics and Molecular Design Group. Jichen joins us from the Shanghai Institute of Organic Chemistry, where he … Read more