Jacob Stuckey (PhD Candidate 2016) and colleagues report in Nature Chemical Biology the first cellularly active chemical probe (UNC3866) for any member of the chromodomain family of proteins that recognize, or “read” methylated lysine. Specifically, the probe inhibits the … Read more
On December 1, 2015, Dr. Samantha Pattenden received word that she is the recipient of a $7500 IBM Junior Faculty Development Award. Congratulations!
We are pleased to announce that our very own Nate Hathaway has been named a 2016 recipient of the AACP New Investigator Award. Nate’s award centers around the “Development of Novel Inhibitors of Mammalian Heterochromatin Gene Repression.” View all the … Read more
Lindsey James, Steve Headey (Monash University, Australia), Ken Pearce and Stephen Frye have been awarded a grant by the PharmAlliance Research Working Group and Deans to assist in funding preliminary data for the project “Discovery of Inhibitors for the Methyl-Lysine … Read more
Ken Pearce and collaborator Channing Der (Pharmacology) received a UNC Lineberger Development Research Grant for their proposal, “A Cellular Screen Utilizing the Global Protein Stability Method to Identify Chemical Probes that Expedite the Myc-degradation Pathway.” (Jan. 2016)
The Center for Integrative Chemical Biology and Drug Discovery welcomes Jichen Zhao to the Medicinal Chemistry Group and Gwonchan Yoon to the Computational Biophysics and Molecular Design Group. Jichen joins us from the Shanghai Institute of Organic Chemistry, where he … Read more
