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How to Find Us

The Center for Integrative Chemical Biology and Drug Discovery is located on the third floor in Marsico Hall near the intersection of Mason Farm Road and West Drive on the UNC campus in Chapel Hill.


CICBDD Mailing Address:

125 Mason Farm Road
Chapel Hill, NC 27599-7363

CICBDD Shipping Address:

Marsico Hall, Room 3015
125 Mason Farm Road
Chapel Hill, NC 27599-7363

Phone: 919-843-0766 (Administration)
Fax: 919-843-8465

Email Us
CICBDD Parking

Visitor parking is available in the Dogwood Deck across from UNC Hospitals on Manning Drive. The entrance to the Dogwood Deck is on East Drive.

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Contact Us

sara_leslieSara Leslie
Business Operations Officer
CB #7363
3201 Marsico Hall
125 Mason Farm Rd.
Chapel Hill, NC  27599-7363

dottie_forthmanDottie Forthman
Administrative Support Specialist
3011 Marsico Hall
125 Mason Farm Rd.
Chapel Hill, NC 27599-7363

About Marsico Hall

Marsico Hall opened in the spring of 2014 and houses research laboratories from both the School of Medicine and the UNC Eshelman School of Pharmacy. The Centers’ labs (~10,000 sq ft) and offices are on the third and fourth floors of the nine-story building. Access to parts of the facility is controlled so appointments are recommended.

Marsico Hall was dedicated on March 27, 2014, and is named in honor of Thomas F. Marsico of Denver, Colorado, for his lifetime contributions to health-care programs at UNC.

What We Do

The Center’s research explores small molecule probes, drug leads, and target validation via proposals from UNC faculty and Center-initiated projects in chromatin chemical biology.

“The Center will be an innovative and sustainable scientific force in the creation of chemical probes, drug candidates, assay technologies, and computational approaches to advance understanding of biological mechanisms and place UNC at the forefront of translational medicine.”

Goals Of The Center

  • Enable interrogation of biology with small molecules resulting in novel insights into human disease with a focus on oncology
  • Create the leading research program in chemical biology of chromatin regulation
  • Provide student and faculty training and enrichment in the areas of expertise within the Center
  • Create intellectual property to support translational drug discovery
  • Establish collaborations and funding base such that the Center is sustainable

Current Openings

Postdoc-James Lab

Computational Biophysics and Molecular Design Work

Computational Biophysics and Molecular Design Work


Balloons temporarily hold gases in a chemical hood. These blue balloons were decorated, one with the word TAR and the other with the word HEELS.

Having a little fun in the hood!


The Area

Life in North CarolinaSouthpoint Mall

North Carolina has a diverse landscape from the Appalachian Mountains to the Piedmont to the Outer Banks, Whether you enjoy swimming, running, hiking or cycling, you can find it in North Carolina.  In the center of it all is Chapel Hill, the home of The University of North Carolina-Chapel Hill.


Chapel Hill is one of few places that offers world-class research opportunities with a high quality of life and a warm climate. Chapel Hill, and its adjoining town Carrboro, are part of the Research Triangle region of North Carolina, along with the cities of Durham and Raleigh. It’s often said that the region has the highest concentration of PhD’s due to the area’s Universities (UNC, NC State , Duke ) and Research Triangle Park. The area is renowned for its hospitality, its food, and its music scene.

There are lots of outdoor activities in the area, including cycling, running, and swimming (hence all the triathletes). Chapel Hill is also ~2 hours from the Atlantic Ocean, ~2 hours from the mountains, and ~4.5 hours from the Great Smoky Mountains.

Greetings from Chapel Hill Mural

What to do in Chapel Hill

UNC-CH Visitors Guide

Chapel Hill Public and Cultural Arts Office

Comprehensive Information available from the
Chapel Hill-Orange County Visitors Bureau
 slide_franklin_street (airial view)

The Chapel Hill Historical Society

University of North Carolina
(including Ackland Art Museum and more)

Cats Cradle (live music)

Merritt’s Grill (best BLT you’ve ever had)

Carrboro Farmer’s Market (the hub of a vibrant local food community)

The Preservation Society of Chapel Hill at the Horace Williams House

The Arts Center


Old Well

Chapel Hill's Carolina Blue Fire Hose Truck with the Tar Heel on Back





Konstantin PopovKonstantin Popov Joins CICBDD as Director of Computational Biophysics



Please join us in welcoming Dr. Konstantin Popov as Associate Professor in the Division of Chemical Biology and Medicinal Chemistry, and Director of Computational Biophysics, here in the Center.

Konstantin comes to us from a Research Assistant Professor position in the Department of Biochemistry and Biophysics at UNC. His research expertise is at the interface of computational and structure-guided chemical probe and drug discovery, which is a vital part of the mission of the CICBDD.

Konstantin received his PhD in polymer physics and chemistry from Moscow State University, Russia in 2009. While getting his PhD, he worked part time as a research associate at the Schlumberger Moscow Research Center. He subsequently received a year of postdoctoral training in nano drug delivery research at Northwestern University under the mentorship of Professor Monica Olvera de la Cruz. Following four additional years of postdoctoral research applying computational methods to cell motility at the University of Maryland at College Park, under the supervision of Professor Garegin Papoian, Dr. Popov was appointed as Research Assistant Professor at the Department of Biochemistry and Biophysics at UNC in 2014. At UNC he has established numerous collaborations including ones with Professors Alexander Tropsha and Andrew Lee within the Eshelman School of Pharmacy, as well as numerous other faculty in the Center and across campus. With these latter collaborations, he has been heavily involved in several recent grant applications and awards toward new anti-viral therapeutics. He will also be an important contributor to several ongoing programs toward Alzheimer’s and cancer chemical probes and therapeutics.

We are looking forward to having Konstantin be a central researcher, collaborator, and leader here in the Center.