Dr. Stephen Frye virtually presented a seminar titled “Allosteric antagonists of methyl-lysine reader domain interactions with DNA/RNA” for the Department of Chemistry at Scripps Research Institute. Dr. Frye has an extensive background and success in chemical probe development and drug … Read more
Thursday November 5, 2020 “Technology Development for Inhibitor Discovery of Chromatin Associated Proteins Linked to Lysine Methylation” Seminar based upon the doctoral dissertation of Justin M. Rectenwald under the direction of Dr. Ken Pearce and Dr. Stephen Frye. Abstract … Read more
Xiaodong’s most impactful project focuses on discovery of potent and selective TAM tyrosine kinase inhibitors. This project has resulted in a clinical candidate that is progressing through Phase 1 studies at UNC and Emory University. Dr. Wang led the medicinal … Read more
Cathy Anderson, a graduate student in the UNC Department of Biochemistry and Biophysics, has been awarded the NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00). Anderson was selected as the UNC nominee last fall and has now been awarded this … Read more
The goal of the Rapidly Emerging Antiviral Drug Discovery Initiative (READDI) is to develop antiviral drugs for epidemic and pandemic viruses. In the current environment, READDI is focused exclusively on identifying and developing antiviral drugs to treat and/or prevent COVID-19 … Read more
“It’s great to see the collaborative chromatin-focused science in the CICBDD recognized for its translational potential. Nate and Lindsey have created innovative programs that can hopefully lead to impact in patients with this initial support from the EII.” Stephen V. … Read more
Justin Rectenwald, graduate student and lab member of Dr. Stephen Frye and Dr. Ken Pearce June 11, 2019 Justin Rectenwald has been awarded the 2019 Diane Harris Leadership Award for exemplary public service as a doctoral student in the … Read more
Veronica Correa October 1, 2019 A group of researchers from the University of North Carolina at Chapel Hill are part of a new research proposal to create chemical and biological tools to explore novel molecular targets related to … Read more
Chemical Biology and Medicinal Chemistry Brittany Jennings October 30, 2019 Lindsey Ingerman James, Ph.D. Lindsey Ingerman James, Ph.D., with the UNC Eshelman School of Pharmacy is interested in epigenetic abnormalities that lead to cancer. For example, misregulation of the NSD2 … Read more
Veronica Correa November 27, 2019 Nathaniel Hathaway, Ph.D., a researcher at the UNC Eshelman School of Pharmacy’s Division of Chemical Biology and Medicinal Chemistry, Center for Integrative Chemical Biology and Drug Discovery and the Lineberger Comprehensive Cancer Center, was published … Read more
Chemical Biology and Medicinal Chemistry Brittany Jennings December 18, 2019 Alliance Between UNC-Chapel Hill and Deerfield intends to advance select Carolina innovations toward a possible new treatment against multiple myeloma Lindsey Ingerman James, Ph.D. Pinnacle Hill, the research and development … Read more
