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Xcovery Acquires Meryx

January 14, 2022

Xcovery Acquires Majority Controlling Stake in Meryx Pharmaceuticals December 07, 2021 08:00 AM Eastern Standard Time PALM BEACH GARDENS, Fla.–(BUSINESS WIRE)–Xcovery Holdings, Inc., an oncology focused bio-pharmaceutical company, is proud to announce the acquisition of a majority and controlling stake … Continued

Stephen Frye receives Maximizing Investigators’ Research Award

May 14, 2021

Tops $2 million, supports small molecule research to identify new approaches to modulating drug target Brittany Jennings March 26, 2021   Each day, Stephen Frye, Ph.D., works to identify pharmacologic approaches to intervene in novel drug targets within stephen_fryethe human … Continued

Spotlight on Dr. Samantha Pattenden and the Pattenden Lab

May 14, 2021

Dr. Samantha Pattenden, Associate Professor, joined the CICBDD in 2010 as a Postdoctoral Research Associate and in 2015 was promoted to Assistant Professor, Director of Applied Epigenetic Screening Technologies. In 2017 she co-founded Triangle Biotechnology, Inc. with Dr. Paul Dayton … Continued

Justin M. Rectenwald Successfully Defends Thesis

October 30, 2020

Thursday November 5, 2020 “Technology Development for Inhibitor Discovery of Chromatin Associated Proteins Linked to Lysine Methylation” Seminar based upon the doctoral dissertation of Justin M. Rectenwald under the direction of Dr. Ken Pearce and Dr. Stephen Frye.   Abstract … Continued

Anderson Earns National Cancer Institute Award

August 7, 2020

Cathy Anderson, a graduate student in the UNC Department of Biochemistry and Biophysics, has been awarded the NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00). Anderson was selected as the UNC nominee last fall and has now been awarded this … Continued

Pinnacle Hill Announces First Project Agreement

March 23, 2020

Chemical Biology and Medicinal Chemistry Brittany Jennings December 18, 2019 Alliance Between UNC-Chapel Hill and Deerfield intends to advance select Carolina innovations toward a possible new treatment against multiple myeloma Lindsey Ingerman James, Ph.D. Pinnacle Hill, the research and development … Continued

Skrajna Awarded American Cancer Society Postdoc Fellowship

January 25, 2019

It is a great honor and accomplishment for Aleksandra to receive this competitive ACS postdoctoral fellowship. She was selected among the top applicants based on her past research accomplishments, her research plans for her postdoctoral studies, and her promise as … Continued

ACS BioChemistry Publishes TAF1 Paper

April 6, 2018

  Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1 Junghyun L. Suh† , Brian Watts‡, Jacob I. Stuckey†§, Jacqueline L. Norris-Drouin†, Stephanie H. Cholensky†, Bradley M Dickson†∥ , Yi An†, Sebastian Mathea⊥▼, … Continued

A few minutes with Stephen Frye, PhD

March 12, 2018

Recently Laura Oleniacz, UNC Lineberger Comprehensive Cancer Center, interviewed Stephen Frye to feature highlights of his accomplishments on their Facebook page.  Open this link for a  peek.  Consider posting it on your own FB pages, or even donating to the … Continued

Target class drug discovery

October 19, 2017

Three members of CICBDD (Center for Integrative Chemical Biology and Drug Discovery) provide commentary to Nature Chemical Biology, October 2017 edition.  Read the article here.

New roles in CICBDD for Samantha Pattenden and Lindsey James

October 6, 2017

Stephen Frye has announced new Director roles in the CICBDD for Samantha Pattenden and Lindsey James based on their ongoing contributions to the mission of the Center.  These titles will make visible their role in fostering collaborations with other UNC … Continued

Undergraduate Summer Research

August 7, 2017

The Graduate School at UNC-CH hosted the Summer Undergraduate Pipeline Research Symposium. It brought students and their mentors together to showcase the work that the 139 undergraduates from across the country participated in over the last few weeks.  Representing 14 … Continued

Jeffrey Aube Receives the Edward Leete Award

August 7, 2017

Edward Leete Award Purpose To recognize outstanding contributions to teaching and research in Organic Chemistry Nature The award will be presented no more than biennially during the fall national meeting of the American Chemical Society. The Award consists of a … Continued

Samantha Pattenden Awarded Grant from NCBC

March 23, 2017

Samantha Pattenden has led a team of UNC scientists to a successful Institutional Development Grant application from the North Carolina Biotechnology Center for the project Advanced Acoustic Sonication for High Throughput Nucleic Acid Fragmentation, Biospecimen Processing, and Drug Discovery.   The … Continued

Oliver Bell to Visit UNC

March 9, 2017

Oliver Bell, PhD IMBA – Institute of Molecular Biotechnology   Oliver Bell will visit UNC on April 10 and 11.  At 4 PM on Tuesday, April 11, he will present a seminar in Bioinformatics 1131 titled,  “The silent Polycomb revolution – … Continued

Congratulations to Tigran Abramyan

February 1, 2017

Congratulations to Tigran Abramyan who has been approved for a domestic travel award from the Office of Postdoctoral Affairs (OPA).  Tigran will attend the 253rd ACS National Meeting & Exposition, to present research conducted in collaboration with the Lineberger Comprehensive … Continued

David H. Thompson, PhD to Visit CICBDD

December 9, 2016

   Read: His tagged cryocapture – Langmuir 2016 The Center for Integrative Chemical Biology and Drug Discovery Presents: David H. Thompson, PhD Professor – Organic Chemistry Purdue University   “Development of New Tools for Accelerated Protein Structure Determination and Reaction … Continued

GE IN Cell Analyzer 2200

October 25, 2016

Thanks to the North Carolina Biotechnology Center Institutional Development Grant (NCBC IDG) program, the CICBDD and the Hooker Imaging Core were awarded $200,000 to support the purchase of a high content cell imaging system.  Matching funds for the instrument were … Continued

NCI Renews Partnership with UNC to Seek New Cancer Drugs

October 14, 2016

October 6, 2016 By David Etchison The University of North Carolina at Chapel Hill will pursue treatments for specific cancer targets as a specialized member of the National Cancer Institute’s renewed Experimental Therapeutics, or NExT, program. Because of its unique … Continued

New Research Funding

October 6, 2016

R01 Stephen Frye, PhD and Lindsey James, PhD will collaborate with PI Matt Redinbo, PhD on his R01 grant from NCI entitled Microbiome-Targeted Probes to Eliminate Chemotherapy-Induced GI Toxicity.  The overarching hypothesis is that microbial enzymes expressed by the GI … Continued

Rob McGinty Joins CBMC, CICBDD

August 3, 2016

Rob was born in Muscatine, Iowa, and adds “but spent all of my school age years in Portland, Oregon. Since then I have been an academic nomad with undergraduate studies at Iowa State University followed by graduate work in the … Continued

UNC Eshelman School of Pharmacy Celebrates Top Ranking

March 31, 2016

Story by Susan Hudson, University Gazette Video by Carly Swain, Office of Communications and Public Affairs Published March 30, 2016   Read the article in its entirety here. http://www.unc.edu/spotlight/pharmacy-school-celebrates-top-ranking/

Sarah Scarry Appointed Research Assistant Professor

March 21, 2016

Dr. Sarah Scarry was appointed to the position of Research Assistant Professor in the Division of Chemical Biology and Medicinal Chemistry in the UNC Eshelman School of Pharmacy.  Dr. Scarry will be expanding her medicinal chemistry expertise into the arena … Continued

2016 Recipient of the AACP New Investigator Award

January 14, 2016

We are pleased to announce that our very own Nate Hathaway has been named a 2016 recipient of the AACP New Investigator Award. Nate’s award centers around the “Development of Novel Inhibitors of Mammalian Heterochromatin Gene Repression.”  View all the … Continued

PharmAlliance Grant 2016

January 14, 2016

Lindsey James, Steve Headey (Monash University, Australia), Ken Pearce and Stephen Frye have been awarded a grant by the PharmAlliance Research Working Group and Deans to assist in funding preliminary data for the project “Discovery of Inhibitors for the Methyl-Lysine … Continued